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姓名: 杨一鸣

性别: 女

职称: 副教授

是否博导: 否

最高学历: 研究生

最高学位: 博士

电话: 17386868971

邮箱: ym_yang@jlu.edu.cn

详细情况

所在学科专业:

细胞生物学

研究方向:

1. 溶酶体离子通道功能与相关疾病2. 膜融合蛋白的功能及膜融合机制

讲授课程:

本科生:细胞生物学,细胞生物学实验

教育经历:

2000.9-2005.7 大连医科大学,临床医学,本科生/医学学士

2006.9-2013.12 中国医科大学,生物学,研究生/理学博士

工作经历:

2014.1-2015.6 东北师范大学,博士后研究

2015.6-2020.11 加拿大达尔豪斯大学 博士后研究

2021.8-至今 吉林大学 biwn必赢 副教授

科研项目:

1. 吉林省教育厅科学技术项目5万元;项目负责人

2. 吉林大学人才引进科研启动经费4万元;项目负责人

3. 吉林大学学术骨干引进科研配套经费25万元;项目负责人

学术论文:

1. Yiming Yang, Nandini Nagarajan Margam. Structural insights into membrane fusion mediated by convergent small fusogens. Cells. 2 IF:6.6

2. Yiming Yang, Gerard Gaspard, Nichole McMullen, Roy Duncan. Recombination Events Driving Polycistronic Genome Segment Evolution and FAST Protein Diversity During Fusogenic Orthoreovirus Speciation. Viruses. 2IF:5.0

3. Yiming Yang#, Xingjian Zhai#, Yassine El Hiani. TRPML1-Emerging Roles in Cancer. Cells. 2020. 2IF:6.6

4. Yiming Yang, Mengnan Xu, Xiaojuan Zhu, Jing Yao, Bing Shen, Xian-Ping Dong. Lysosomal Ca2+ release channel TRPML1 regulates lysosome size by promoting mTORC1 activity. Eur J Cell Biol. 2019. 3IF: 4.5

5. Mengnan Xu#, Shekoufeh Almasic#, Yiming Yang#, Chi Yan#, Andra Mihaela Sterea, Alia Kazim Rizvi Syeda, Bing Shen, Clements Richard Derek, Peng Huang, Shashi Gujar, Jun Wang, Wei-Xing Zong, Mohamed Trebak, Yassine El Hiania, Xian-Ping Dong. The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways. Cell Calcium. 2019. 2IF:6.8

6. Xue Sun, Yiming Yang, Xi Zoë Zhong, Qi Cao, Xin-Hong Zhu, Xiaojuan Zhu & Xian-Ping Dong. A negative feedback regulation of MTORC1 activity by the lysosomal Ca2+ channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism. Autophagy. 2018. 1IF: 16.02

7. Zhong XZ, Yang Y, Sun X, Dong XP. Methods for monitoring Ca2+ and ion channels in the lysosome. Cell Calcium. 2017. 2IF:6.8

8. Qi Cao#, Yiming Yang#, XiZoë Zhong, and Xian-Ping Dong. The lysosomal Ca2+ release channel TRPML1 regulates lysosome size by activating calmodulin. J Biol Chem. 2017. 2IF: 5.1

9. De S Shang, Yi M Yang, Hu Zhang, Li Tian, Jiu S Jiang, Yan B Dong, Ke Zhang, Bo Li, Wei D Zhao, Wen G Fang, Yu H Chen. Intracerebral GM-CSF contributes to transendothelial monocyte migration in APP/PS1 Alzheimer's disease mice. J Cereb Blood Flow Metab. 2016. 2IF: 6.2

10. Yiming Yang#Deshu Shang#, Weidong Zhao, Wengang Fang, Yuhua Chen. Microglial TNF-α-dependent elevation of MHC class I expression on brain endothelium induced by amyloid-beta promotes T cell transendothelial migration. Neurochem Res. 2013 Nov; 38 (11): 2295-304. 3IF: 4.0

著作教材:

获奖情况:


社会兼职:

中国细胞生物学学会会员


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